Perinatal varicella.
نویسندگان
چکیده
In 1947, LaForet and Lynch first described the association between maternal infection by Varicellazoster virus during the beginning of gestation and congenital anomalies in the newborn(1). Today varicella during pregnancy is a very rare condition. Primary infection by varicella during gestation is estimated to affect one to seven per 10 thousand pregnant women(2). The Varicella-zoster virus is transmitted to the fetus mainly through the placenta, as a result of viremia promoted by primoinfection or viral reactivation. The risk of maternal-fetal transmission ranges from 0.5 to 6.5%(3). Varicella is considered a congenital syndrome when the pregnant woman is infected between zero and 20 weeks of gestation. Perinatal varicella occurs in newborns up to 10 days after birth(3-6). The congenital varicella syndrome is characterized by embryofetopathy, including cicatricial lesions on the skin, limb hypoplasia, muscle atrophy, clubfoot, intrauterine growth restriction, microcephalus, cerebellar and cortical
منابع مشابه
Varicella Exposure in Neonatal Intensive Care Unit in a Low Resource Country: Successful Prophylaxis with Intravenous Immunoglobulins
Background: Varicella-zoster infection is a serious and potentially fatal disease, especially among newborns.Several studies have described postnatal varicella zoster exposure among neonates and reported on the efficacy of varicella-zoster immunoglobulins (VZIG) used as post-exposure prophylaxis. Unfortunately, VZIG is not available in Jordan. A limited number of studies have investigated the e...
متن کاملReview of varicella-zoster virus infections in pregnant women and neonates
Even though varicella is rare in pregnancy, the disease can lead occasionally to disastrous illnesses for both the mother and her neonate. By contrast, normal zoster is not associated with special problems during pregnancy and perinatal period. Pregnant women, who contract varicella, are at risk of varicella pneumonia which must be regarded as medical emergency. At any stage during pregnancy, c...
متن کاملAustralian Paediatric Surveillance Unit annual report, 2013.
This report provides an update on the surveillance conducted by the Australian Paediatric Surveillance Unit (APSU) during the period January to December 2013. The APSU facilitates national active surveillance of uncommon diseases of childhood including selected communicable diseases. This report includes data on the following conditions: acute flaccid paralysis (AFP), congenital cytomegalovirus...
متن کاملSeroprevalence of varicella antibodies in healthcare workers in Imam Reza hospital of Kermanshah-Iran
The objective of this study was to assess the seroprevalence of varicella antibodies in healthcare workers and students of healthcare professions and to determine the validity of the self-reported varicella and zona history for detecting susceptible subjects. Personnel of Imam Reza hospital (Kermanshah-Iran) and students were recruited and a 5 mL blood sample was obtained from all participants....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Einstein
دوره 8 1 شماره
صفحات -
تاریخ انتشار 2010